The higher education systems established by the State of California – the University of California, the California State University, and the California community colleges – are known worldwide, collectively operate nearly 150 institutions, and enroll nearly three million students. They are led by boards charged with advancing the public interest and stewarding $20 billion in state funds in the process. What role does innovation play in these massive systems’ strategies? How are these boards responding to rapid changes in technology? How should innovators and entrepreneurs influence the path forward?